Local Anesthetic Apis Pain Killer Drug Procaine Hydrochloride Procaine HCl
|Place of Origin:||China|
|Min.Order Quantity:||50 Grams|
|Price:||USD $0.1 - $0.2 / Gram|
|Appearance||A white crystalline powder or colourless crystals||Complies|
|Identification||IR Absorption/Reaction of chlorides /Reaction of primary aromatic amines||Complies|
|Color and clarity of solution||Colorless and clear||Conforms|
|pH (Acidity)||5.0~6.5 (≤0.02NNaOH0.5ml)||5.5/0.2ml|
|Loss on drying||≤0.5%||0.16%|
|Assay(C 13 H 20 N 2 O 2 .HCl)||99.0~101.0%||99.65%|
Procaine is a kind of local anesthetics. With low toxicity but quick and safe effects, procaine is suitable for local anesthesia, applied to the eye, ear, nose, teeth and other department operation, used for infiltration anesthesia, anesthesia and closed therapy supervisor. Procaine is also used in the production of procaine penicillin.
Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.